January 29, 2023

Vybirai Ka

Specialists In Health

Bioscience and well being know-how sector statistics 2021

Bioscience and well being know-how sector statistics 2021

1. Details

  • The variety of life sciences companies working within the UK has remained broadly comparable since 2018, with a complete of 6,548 in 2021. These companies had a complete of seven,599 websites within the UK, a 3% enhance in comparison with 2020.

  • There have been 282,000 individuals employed within the UK life sciences sector in 2021, a relative enhance of 4% in comparison with 2020. Employment in life sciences within the UK has seen a steady upward pattern between 2012 and 2020.

  • Companies within the UK life sciences business generated £94.2 billion in turnover in 2021, a 9% enhance from the £86.4 billion (in 2021 costs) raised in turnover in 2020. Turnover has seen an upward pattern total since 2013 however has elevated at a sharper charge between 2019 and 2021.

  • There are 4 sectors working inside the life sciences business (biopharmaceutical core, biopharmaceutical service and provide, medical know-how core and medical know-how service and provide). The sector with the very best proportion of websites and employment was the medical know-how core sector, accounting for 44% of websites and 40% of employment in 2021. This sector has constantly accounted for the very best variety of websites and employment between 2009 and 2021.

  • The sector that generated the very best turnover in 2021 was the biopharmaceutical core sector, accounting for 43% of the entire turnover generated throughout the life sciences business. This was adopted by the biopharmaceutical service and provide sector and medical know-how core sector which every accounted for a share of 25% of turnover in 2021.

  • The South East continues to be the UK area with the very best share of each life sciences business employment and turnover, accounting for twenty-four% of whole employment and 30% of whole turnover in 2021.

2. Introduction

This report accommodates evaluation of tendencies within the UK life sciences business, masking the biopharmaceutical and medical know-how principal sectors. The information doesn’t embrace industrial biotechnology, animal well being, not-for-profit organisations, public funded establishments or universities. The three foremost measures of financial contribution and business construction contained on this report are:

  • employment – the variety of individuals employed by life sciences companies
  • turnover – the sum of money taken by companies inside scope of life sciences sector actions
  • variety of companies and their websites – the variety of life sciences companies and their websites registered within the UK

The evaluation on this report covers the financial exercise of companies that target the invention, improvement and advertising and marketing of recent therapies and medical gadgets, known as ‘core’ companies, in addition to companies working within the specialist service and provide chains which can be key components of the ecosystem. A segmentation strategy is utilized that allows an in depth evaluation of the product and repair classes that make up the business.

The BaHTSS sequence publishes information 1 12 months in arrears and this iteration of the report (masking information as much as and together with the top of the monetary 12 months in 2021) was initially printed on 1 December 2022. The information on this report is aggregated by way of monetary years, however is labelled because the calendar 12 months corresponding with the top of the monetary 12 months (for instance, the monetary 12 months 2020/21 is labelled as 2021). Extra data on the information and strategies used on this report may be discovered within the accompanying background high quality and person information.

This report can be accompanied by:

3. Publication updates

3.1 New additions

This report publishes information on employment and turnover from life sciences companies working within the UK at native authority district degree for the primary time.

3.2 Methodology adjustments

A number of adjustments have been made to the methodology behind the statistics this 12 months, together with:

  • Additional analysis was carried out this 12 months to establish companies which have substantial ranges of exercise within the subject of genomics. This has resulted in additional companies being tagged with the genomics classification codes. All figures on this report embrace a backdated timeseries to cowl these companies.
  • Further work has been undertaken within the 2021 publication to enhance the accuracy and protection of enterprise measurement classification and enterprise possession classification. This has resulted in additional correct identification of companies which can be small and medium-sized enterprises (SMEs), and companies which can be UK-owned or overseas-owned. This work has been utilized to the 2021 solely, and because of this information for earlier years will not be obtainable inside this report.
  • This publication solely consists of life sciences websites working within the UK and excludes any working within the UK’s crown dependencies. Earlier publications within the BaHTSS sequence consists of websites within the crown dependencies. The time sequence on this report has been backdated retrospectively.

It is strongly recommended to all the time use essentially the most not too long ago obtainable report within the BaHTSS sequence. Extra particulars on these adjustments may be discovered within the accompanying background high quality and person information.

3.3 Revision notices

An error was noticed referring to the turnover timeseries for previous studies for the years 2009 to 2018. The timeseries is revised every year, however the corrections made to resolve this error have meant that the turnover timeseries has been revised by greater than regular on this 12 months’s publication (a lower of as much as 8% in every year between 2009 and 2018). This transformation in turnover may be seen within the biopharmaceutical core and repair and provide sectors.

In 2021, there have been 6,548 companies working within the UK life sciences business over 7,599 websites. These companies employed 282,000 individuals and generated £94.2bn of turnover.

The variety of companies and the variety of websites throughout these companies have each seen an upward pattern since 2009, with 23% extra companies and 32% extra websites working in 2021 in comparison with 2009. Between 2018 and 2021, the variety of companies remained broadly secure however the variety of websites has seen a small enhance in the identical interval. In 2021, there was a 3% enhance within the variety of websites in comparison with 2020. Except for a slight lower between 2016 and 2017, each websites and companies noticed gradual will increase every year previous to 2018, with a extra substantial rise between 2017 and 2018.

Determine 1: variety of companies and websites within the UK life sciences business

Bioscience and well being know-how sector statistics 2021

Equally, employment within the life sciences business has seen an total upward pattern between 2009 and 2021. Employment has seen a sharper enhance since 2019, rising from 262,100 in 2019 to 282,000 in 2021, a rise of 8%. Yr-on-year adjustments have ranged between a lower of two% seen between 2011 and 2012 to a 4% enhance seen between 2014 and 2015 and in addition between 2020 and 2021.

Determine 2: employment within the UK life sciences business

Turnover generated by the life sciences business, adjusted for inflation and primarily based on 2021 costs, elevated every year between 2013 and 2021. This was preceded by a brief interval of declining turnover between 2011 and 2013. Just like tendencies seen in life sciences employment, turnover has additionally seen a sharper enhance in recent times. The best year-on-year enhance in turnover, each in financial and proportion phrases, occurred between 2020 and 2021 with turnover rising by £7.8 billion (a rise of 9%).

Determine 3: turnover generated by the UK life sciences business

5. Life sciences business by sector

5.1 Companies and websites by sector

Some companies might have a number of websites that function in numerous sectors of the life sciences business. On this evaluation, these companies shall be included in every of the enterprise counts for the sectors their websites function in. Because of this the sum of the sector enterprise counts shall be better than the entire variety of companies throughout the life sciences business as an entire. Extra data on companies working over a number of sectors may be discovered within the accompanying background high quality and person information.

In 2021, there have been 4,375 websites working within the core sector, which accounted for 58% of whole life sciences websites. Of those core websites, 995 had been within the biopharmaceutical sector and three,380 had been within the medical know-how sector. This meant that core biopharmaceutical websites accounted for 13% of all life sciences websites in 2021, while medical know-how core websites accounted for 44%.

In 2021, there have been an extra 3,224 websites which specialised within the UK primarily based service and provide sector, which accounted for 42% of life sciences websites. Of those service and provide websites, 1,802 had been within the biopharmaceutical sector and 1,422 had been within the medical know-how sector. This meant that the biopharmaceutical service and provide sector accounted for twenty-four% of all life sciences websites in 2021 and medical know-how service and provide websites accounted for 19%.

All 4 sectors within the business have seen an upward pattern within the variety of websites between 2009 and 2021. The biopharmaceutical sectors have skilled a steeper enhance in comparison with the medical know-how sectors. Though the core medical know-how sector has persistently had the very best variety of websites every year since information assortment started in 2009, this enhance within the variety of biopharmaceutical websites has meant that the general share of websites working within the core medical know-how sector has decreased from 50% in 2009 to 44% in 2021

All 4 sectors noticed will increase within the variety of websites between 2020 and 2021, with the most important absolute enhance seen within the core medical know-how sector, which elevated its websites by 133, or 4%.

Determine 4: variety of life sciences websites by sector

5.2 Trade employment by sector

Employment in core companies was 176,800 in 2021, which accounted for 63% of all life sciences employment. Round two thirds (112,300 individuals) had been employed within the medical know-how core sector, in comparison with 64,500 within the core biopharmaceutical sector.

In 2021, 105,200 individuals had been employed in companies working within the UK primarily based service and provide sector, which accounted for 37% of individuals employed within the life sciences business. In distinction to core companies, many of the employment for service and provide companies was inside the biopharmaceutical sector, which accounted for 71,800 (round two thirds) of the entire 105,200 employed within the service and provide sectors in 2021.

The sector with the very best employment out of the 4 sectors was the core medical know-how sector, which accounted for 40% of employment within the life sciences business in 2021. This has persistently been the sector with the very best share of employment since 2009 and its share of whole life sciences business employment has stayed broadly constant over time.

The biopharmaceutical service and provide sector skilled the steepest proportion enhance in employment between 2020 and 2021, with a rise of 9% in that point interval. This continues the sharp upward pattern that has been seen within the sector since 2015. All different sectors have additionally seen rising employment between 2020 and 2021, however to a lesser extent than the biopharmaceutical service and provide sector.

Determine 5: UK life sciences employment by sector

5.3 Trade turnover by sector

Turnover values on this publication are reported in 2021 costs, utilizing GDP deflators to regulate for inflation.

The core biopharmaceutical sector generated £40.8 billion in turnover in 2021, accounting for 43% of the life sciences business whole. By way of turnover, this sector has persistently been the most important of the 4 sectors yearly since information assortment started in 2009. Turnover generated by the core biopharmaceutical sector was at its highest in 2011 (£43.1 billion), after which turnover decreased yearly till it reached its lowest level at £34.0 billion in 2017. 4 consecutive years of progress since then have introduced turnover above £40.0 billion for the primary time since 2012.

Every of the 4 life sciences sectors noticed will increase in turnover between 2020 and 2021, the most important of which had been seen within the core biopharmaceutical and biopharmaceutical service and provide sectors, whose turnover values elevated by £2.8bn (enhance of seven%) and £2.7bn (enhance of 13%) respectively.

The 2 core sectors have traditionally contributed the vast majority of the life sciences business turnover, though current progress within the biopharmaceutical service and provide sector has closed the hole between this sector and the core medical know-how sector. The general proportion of life sciences business turnover being generated by the 2 core sectors has decreased over time, from 79% in 2009 to 69% in 2021.

Determine 6: turnover generated by the life sciences business by sector

6. Variation throughout the UK

6.1 UK life sciences business employment

The South East had the very best employment of all areas within the UK at 67,000 in 2021, accounting for twenty-four% of all employment within the business. The South East had the very best share of employment persistently between 2009 and 2021. Regardless of this, the share of employment primarily based within the South East has declined barely from 26% in 2009.

The second highest area by way of life sciences business employment in 2021 was the East of England, which accounted for 38,000 (or 13%) of whole employment. Employment on this area noticed a rise of 1% between 2020 and 2021, though employment in 2021 remained decrease than the height of 40,200 seen in 2017.

In 2021, 11% of life sciences business employment was primarily based in London. Employment on this area has typically adopted an upward pattern over time, from 19,300 (which was equal to 9% of the entire business employment) in 2009 to 31,700 in 2021. This enhance in life sciences employment meant that London overtook the North West to turn out to be the UK area with the third highest employment in 2021.

Life sciences business employment elevated sharply between 2019 and 2021, with every particular person area seeing a rise in employment over this time interval. London noticed the very best proportion enhance at 18%. The South East additionally noticed a proportion enhance in employment of 6% in the identical time interval. All areas had greater employment in 2021 in comparison with 2009, with the most important web will increase seen in London, the South East and Yorkshire and the Humber.

Determine 7: proportion of employment within the UK life sciences business by area in 2021

Be aware: the information labels within the chart are rounded to 0 decimals locations however the bars symbolize their unrounded worth

Biopharmaceutical employment

The South East had the very best employment of all areas within the biopharmaceutical sector at 33,000 in 2021, which accounted for twenty-four% of all employment within the business. 17,000 of this employment was within the core sector in comparison with 16,300 within the service and provide sector. In 2021, 26% and 23% of all employment in core biopharmaceutical and repair and provide companies respectively was within the South East.

The East of England was the UK area with the following highest share of biopharmaceutical employment in 2021, accounting for 18% (or 24,200) of the entire. Biopharmaceutical employment within the East of England was at its highest (24,300) in 2016, after which the area noticed 3 consecutive years of reducing employment, adopted by a rise between 2019 and 2021 which introduced biopharmaceutical employment again as much as an identical degree to that seen in 2016.

Employment inside the biopharmaceutical sector in London was at 19,500 in London, accounting for 14% of all biopharmaceutical employment. Employment on this area elevated by 2,700, a proportion enhance of 16%, between 2020 and 2021, which was the most important enhance of all of the UK areas throughout this time interval.

Throughout the complete time interval from 2009 to 2021, the most important regional web enhance in biopharmaceutical employment was seen in London, whose employment elevated by 6,300 (a proportion enhance of 47%). The South East was the one area whose employment decreased over this time interval, from 35,800 in 2009 to 33,300 in 2021.

The native authority districts of the UK with the very best employment within the biopharmaceutical sector in 2021 had been South Cambridgeshire within the East of England area and Cheshire East within the North West at 7,200 and 6,500, respectively. The employment figures for these two districts individually every accounted for round 5% of employment within the biopharmaceutical sector.

Determine 8: distribution of employment within the biopharmaceutical sector by native authority district in 2021

Medical know-how employment

Just like the biopharmaceutical sector, in 2021 the South East had the very best share of employment within the medical know-how sector (consisting of each core and repair and provide companies) with employment at 33,600, accounting for 23% of the sector whole. 25,800 of this employment was within the core sector in comparison with 7,900 within the service and provide sector. In 2021, 23% and 24% of all employment in core medical know-how and repair and provide companies respectively had been within the South East.

Yorkshire and the Humber was the area with the second highest share of employment within the medical know-how sector in 2021, accounting for 14,300 (or 10%) of the sector whole. This area was adopted carefully by the North West and the East of England, the place 13,900 and 13,800 individuals, respectively, had been employed within the medical know-how sector in 2021.

The South East noticed the most important web enhance in medical know-how employment between 2009 and 2021, from 22,300 in 2009 to 33,600 in 2021 (a rise of 11,400). Over the identical time interval, London noticed the most important proportion enhance within the medical know-how sector, with employment doubling from 6,100 to 12,100 between 2009 and 2021.

The native authority districts of the UK with the very best employment within the medical know-how sector in 2021 had been the Vale of White Horse at 3,900 and Leeds at 3,600, which accounted for a share of three% and a pair of% of medical know-how employment respectively.

Determine 9: distribution of employment within the medical know-how sector by native authority district in 2021

6.2 UK life sciences business turnover

Just like employment, the South East was the UK area which generated the very best share of life sciences business turnover, at 30% (or £28.6 billion) in 2021. This was practically double that of the area with the second highest turnover generated (the East of England), whose turnover was valued at £14.6 billion (16% of turnover generated by the business). The South East has persistently generated the very best turnover of all areas, and its share of whole business turnover has elevated over time from 27% in 2009.

The North West and London generated £12.4 billion and £10.8 billion turnover in 2021, accounting for 13% and 11% of the life sciences business whole respectively. These two areas adopted the East of England because the third and fourth highest areas by way of the worth of turnover generated in 2021.

Turnover elevated throughout all areas between 2020 and 2021 besides within the West Midlands, the place turnover noticed a proportion lower by 5%. The most important worth enhance over this era was seen within the South East, the place turnover elevated by £2.5 billion, while Scotland and the East Midlands noticed the very best relative will increase in turnover over the interval of 29% and 18% respectively.

Determine 10: proportion of turnover generated within the life sciences business by area in 2021

Be aware: the information labels within the chart are rounded to 0 decimals locations however the bars symbolize their unrounded worth

Biopharmaceutical turnover

In 2021, the UK area with the very best turnover generated by websites working within the biopharmaceutical sector (consisting of each core biopharmaceutical and biopharmaceutical service and provide sectors) was the South East, accounting for 31%, or £19.8bn, of the biopharmaceutical sector whole. The share of whole biopharmaceutical sector turnover generated on this area has elevated over time from 27% in 2009.

The South East has been the UK area with the very best worth of turnover generated within the biopharmaceutical sector yearly since information assortment started in 2009. Throughout this time interval, the South East’s biopharmaceutical turnover was at its lowest (£13.0 billion) in 2013, after which the area skilled a normal upward pattern, with the very best annual turnover worth of the interval occurring in 2021.

Between 2009 and 2021, the East of England was the second highest area by way of biopharmaceutical turnover yearly besides 2015, when the North West’s turnover exceeded the East of England’s. Other than a reasonably substantial lower in 2015, biopharmaceutical turnover generated within the East of England was broadly constant between 2009 and 2019, after which the area skilled two years of consecutive progress.

Through the interval between 2009 and 2021, the North West recorded its highest turnover for the biopharmaceutical sector in 2021, when turnover was valued at £9.3 billion. This area had beforehand seen a interval of reducing biopharmaceutical sector turnover between 2017 and 2019 (to £7.5 billion by 2019), after which there have been two consecutive years of progress.

In 2021, the native authority district that generated the very best worth of biopharmaceutical turnover was the Vale of White Horse, which accounted for 9% (or £5.5 billion) of whole turnover within the biopharmaceutical sector. This native authority district was carefully adopted by Cheshire East, which generated £5.4 billion (8% of the entire biopharmaceutical sector turnover in 2021).

Determine 11: distribution of turnover within the biopharmaceutical sector by native authority district in 2021

Medical know-how turnover

In 2021, the UK area with the very best turnover generated by websites working within the medical know-how sector (consisting of each core medical know-how and medical know-how service and provide) was the South East, accounting for 29%, or £8.8 billion, of the medical know-how sector whole.

The South East has persistently been the very best UK area by way of medical know-how turnover yearly since information assortment started in 2009. The best 12 months on 12 months enhance (relative and absolute) occurred between 2020 and 2021, when the worth of turnover elevated by £0.6 billion (a proportion enhance of 8%). Equally, London noticed a rise of £0.3 billion (a proportion enhance of 15%), from £1.9 billion in 2020 to £2.2 billion in 2021.

The subsequent highest areas by way of turnover generated by websites working within the medical know-how sector in 2021 had been the East of England and the North West, accounting for £3.3 billion (11% share) and £3.1 billion (10% share) of the entire medical know-how sector turnover. Just like the South East, each areas noticed a rise in medical know-how turnover between 2020 and 2021, with the North West and the East of England seeing will increase of £0.4 billion and £0.3 billion respectively.

In 2021, the highest 4 native authority districts by way of the worth of medical know-how turnover had been all positioned within the South East. The native authority district which generated the very best worth of turnover was Buckinghamshire, which accounted for £1.2 billion (or 4%) of the medical know-how turnover whole in 2021.

Determine 12: distribution of turnover within the medical know-how sector by native authority district in 2021

7. Life sciences business segments

Every web site coated on this publication is allotted a phase primarily based on the exercise carried on the market. A full checklist of those segments and extra particulars on their definitions may be discovered within the accompanying background high quality and person information in part “11. Sector and segmentation classification scheme”.

A small proportion of companies within the database have a couple of web site. As segments are allotted on the web site degree, it’s potential for websites belonging to the identical enterprise to be allotted totally different segments to one another (which means that turnover and employment figures for a single enterprise could also be break up between a number of segments).

7.1 Employment by segmentation

Biopharmaceutical sector

In 2021, the phase inside the biopharmaceutical sector with the very best employment was small molecules (a phase inside the core sector). This phase accounted for 49,200, or 36%, of whole employment within the biopharmaceutical sector. The small molecules phase had greater than double the employment of the second highest phase within the biopharmaceutical sector (contract manufacturing/analysis organisation), the place employment was 23,600 in 2021.

The small molecule phase has constantly had the very best employment of biopharmaceutical websites since 2009. Nonetheless, employment on this phase has decreased since 2009, with employment dropping from 56,100 in 2009 (a proportion lower of 12% between 2009 and 2021). Regardless of the online lower from 2009 to 2021, the small molecule phase began to see an upward pattern from 2019, with employment seeing a proportion enhance of 4% between 2019 and 2021.

All different biopharmaceutical segments with employment over 10,000 in 2021 had been within the service and provide sector. These embrace the contract manufacturing/analysis organisations, reagent, gear and consumable provider websites, and the medical analysis organisation websites.

Determine 13: proportion of employment within the biopharmaceutical sector by phase in 2021

Notes:

  • solely the ten segments with the very best share of employment are proven
  • the information labels within the chart are rounded to 0 decimals locations however the bars symbolize their unrounded worth

Medical know-how sector

In 2021, the medical know-how phase with the very best employment was digital well being. This phase employed 16,400 individuals in 2021 and accounted for 11% of all individuals employed within the medical know-how sector. The digital well being phase has constantly been the phase with the very best employment since 2010 and has seen a steady upward pattern since 2009, with a pointy enhance between 2015 and 2021 (a proportion enhance of 65%). Between 2020 and 2021, employment in digital well being elevated by 12%.

All different segments accounted for lower than 10% of medical know-how sector employment. The subsequent highest segments by way of medical know-how sector employment in 2021 had been single use know-how (10,200), assistive know-how (9,800), and in-vitro diagnostic know-how (9,600).

Determine 14: proportion of employment within the medical know-how sector by phase in 2021

Notes:

  • solely the ten segments with the very best share of employment are proven
  • the information labels within the chart are rounded to 0 decimals locations however the bars symbolize their unrounded worth

7.2 Turnover by segmentation

Biopharmaceutical sector

Just like employment, the core small molecules phase generated the very best turnover of all biopharmaceutical segments, with £34.9 billion of turnover in 2021. This accounted for over half of turnover generated from the biopharmaceutical sector. The small molecule phase has persistently been the highest phase by way of turnover since information assortment started in 2009, though turnover within the phase adopted a downward pattern between 2011 and 2017. After 2017, turnover on this phase noticed 4 consecutive years of progress, with turnover in 2021 reaching its highest worth for the interval between 2009 and 2021.

Following small molecules, the following two highest biopharmaceutical segments by way of turnover had been the reagent, gear and consumables provider phase and the contract manufacturing/analysis organisation phase. Each of those segments function within the service and provide sector and have skilled substantial progress by way of turnover, with rises of 76% and 158% respectively since 2009, and rises of 14% and 30% between 2020 and 2021.

Determine 15: proportion of turnover within the biopharmaceutical sector by phase in 2021

Notes:

  • solely the ten segments with the very best share of turnover are proven
  • the information labels within the chart are rounded to 0 decimals locations however the bars symbolize their unrounded worth

Medical know-how sector

Inside the medical know-how sector, the phase which generated the very best worth of turnover in 2021 was single use know-how. This phase generated £3.0 billion in turnover in 2021, which was 10% of the entire turnover within the medical know-how sector in 2021 and a 53% enhance from 2020. Previous to 2020, turnover on this phase had seen a slight upward pattern between 2009 and 2017 earlier than seeing a brief decline from 2017 to 2019.

Following single use know-how, the following two highest medical know-how segments by way of the worth of turnover generated in 2021 had been in vitro diagnostic know-how and digital well being (producing £2.6 billion and £2.0 billion respectively), each of that are additionally inside the core sector. Like single use know-how, turnover generated inside the in vitro diagnostic phase noticed substantial progress between 2020 and 2021, rising by 46%.

Inside the service and provide sector, the reagent, gear and consumables provider additionally generated a considerable quantity of turnover in 2021 (£1.9 billion), a 16% enhance on the earlier 12 months.

Determine 16: proportion of turnover within the medical know-how sector by phase in 2021

Notes:

  • solely the ten segments with the very best share of turnover are proven
  • the information labels within the chart are rounded to 0 decimals locations however the bars symbolize their unrounded worth

8. Manufacturing and analysis exercise in life sciences websites

On this part of the report, turnover and employment figures relate to websites the place any manufacturing or R&D exercise takes place. A few of these websites will undertake sorts of work along with manufacturing or analysis, and due to this fact employment and turnover from these websites consists of contributions from non-manufacturing or non-research actions.

Some websites will undertake each manufacturing and R&D actions, which means that the figures on turnover and employment for every of those websites will not be mutually unique.

8.1 Manufacturing websites

There have been 2,068 websites in 2021 concerned within the manufacturing of life sciences merchandise throughout the UK. The variety of manufacturing websites has seen a slight downward pattern since 2013, when the variety of websites concerned in manufacturing was at its highest (2,193) for the interval between 2009 and 2021. In 2021, 27% of the entire variety of websites working in life sciences business had been concerned in manufacturing. This proportion has declined year-on-year since 2009, when 37% of websites had been engaged in manufacturing exercise. The variety of websites not engaged in manufacturing exercise has seen a steady upward pattern between 2009 and 2020, which means that the entire variety of websites throughout the life sciences business has seen an total upward pattern even supposing manufacturing websites have declined in quantity.

The area with the very best share of producing websites was the South East, with 15% of websites being primarily based within the area in 2021. Regardless of the South East having the very best proportion of producing websites, this proportion is lower than the South East’s share of all life sciences websites (18% in 2021). Different areas which additionally had a considerable share of the UK’s websites had been Yorkshire and the Humber, the East of England, the West Midlands, and the East Midlands, every accounting for over 10% of producing websites in 2021. London by comparability solely accounted for six% of producing websites in 2021.

In 2021, employment at websites engaged in manufacturing actions was at 115,200, a relative enhance of three% from 2020. Employment at manufacturing websites has elevated total between 2009 and 2021 and has broadly adopted an upward pattern in distinction to the variety of websites. Regardless of this, there have been durations throughout this timeframe when employment declined, most notably between 2011 and 2014, and between 2017 and 2019. Employment elevated notably between 2019 and 2021, from 109,800 to 115,200 (a rise of 5,400, or 5%).

The area with the very best share of employment at manufacturing websites was the South East, with a share of 21% in 2021. This was considerably greater than the share of the area with the second highest employment, the East of England, which accounted for 12% of employment in 2021. In contrast, London accounted for less than 3% of employment at manufacturing websites.

Manufacturing websites generated £35.1bn of turnover in 2021, up from £31.6bn in 2020 – a relative enhance of 11%. Turnover generated from manufacturing websites has fluctuated between 2009 and 2021 however there was an total upward pattern between 2015 and 2021 with a sharper rise between 2019 and 2021.

Just like the variety of websites and employment, the South East was the UK area which generated the very best worth of turnover from websites engaged in manufacturing exercise in 2021, a place it has held persistently since 2009. Websites within the South East generated 23% of all turnover in 2021, though this proportion has declined from 30% in 2014 (the very best share between 2009 and 2021). Websites within the East of England additionally accounted a excessive proportion of the turnover generated by manufacturing websites, at 19% in 2021. In contrast, websites within the London area solely accounted for two% of the entire turnover generated from manufacturing websites.

Determine 17: variety of websites engaged in manufacturing exercise and variety of websites not engaged in manufacturing exercise

8.2 Analysis and improvement (R&D) websites

In 2021, there have been 2,428 life sciences websites within the UK that engaged in R&D exercise. The variety of websites engaged in R&D exercise has seen a notable upward pattern between 2009 and 2021. The proportion of whole UK websites working within the life sciences business that engaged in R&D exercise has remained broadly secure since 2009, with 32% of websites partaking in R&D exercise in 2021.

The areas with the very best share of websites with R&D exercise in 2021 had been the South East and the East of England, with 18% of whole R&D websites primarily based in every area. That is in line with the South East area’s share of all life sciences websites in 2021 (additionally 18%), however greater than the East of England area’s share of all life sciences websites (15%). London had the third highest share of websites engaged in R&D exercise at 15% in 2021.

In 2021, R&D websites reached employment of 96,800, a relative enhance of 5% from 2020. Employment at websites engaged in R&D exercise broadly adopted an upward pattern after 2014 and noticed a sharper rise between 2019 and 2021.

The area with the very best share of employment at websites engaged in R&D exercise was the South East, with a share of 25% in 2021. The East of England additionally accounted for a considerable proportion of employment at R&D websites in 2021, with a share of 19%. London was the UK area with the third highest employment at websites engaged in R&D exercise, with a share of 10% in 2021.

R&D websites generated £29.2 billion of turnover in 2021, up from £26.4 billion in 2020, a relative enhance of 11%. For the interval between 2009 and 2021, turnover generated from R&D websites was at its lowest in 2015, at £21.5 billion, after which turnover elevated every year, with the most important enhance occurring between 2020 and 2021.

Just like the variety of websites and employment, the South East has persistently been the UK area which generated the very best whole turnover for R&D websites since 2015. Between 2009 and 2014 the East of England had the very best proportion of websites engaged in R&D exercise. The South East’s share of turnover generated at R&D websites has grown constantly every year, from 26% in 2009 to 43% in 2021. The share of R&D web site turnover held by the South East in 2021 was extra substantial than the area’s share of R&D websites and R&D employment (18% and 25%, respectively). Websites within the East of England additionally generated a excessive proportion of the turnover generated by R&D websites, at 21% in 2021. In contrast websites within the London area solely generated 7% of the entire turnover generated from R&D websites.

Determine 18: variety of websites engaged in R&D exercise and websites not engaged in any R&D exercise

9. Genomics websites

Genomics is an interdisciplinary subject of science and know-how targeted on the research of genomes. On this evaluation the main focus is on the research of the human genome and the applying of the ensuing information to human well being. Because the instigation of the Human Genome Venture in 2001, the sphere and its purposes have grown.

On this evaluation, websites with genomics exercise are assigned a degree 1 and degree 2 genomics classification. Extra particulars on the classes utilized in these classifications may be discovered within the accompanying background high quality and person information in part “11. Sector and segmentation classification scheme”. This classification is totally separate from the sector/phase descriptions additionally assigned to websites.

In 2021, there have been 96 websites that engaged in genomics exercise, using 4,100 individuals. The variety of websites has constantly elevated year-on-year from 33 websites in 2009.

Employment has seen substantial will increase since 2009 with sharp will increase year-on-year since 2017. There was a 12% rise in employment at websites with genomics exercise between 2020 and 2021.

The genomics space with the very best employment was sequencing, which entails decoding the order of the nucleotides in a genome. There have been 2,300 individuals employed at websites engaged primarily in sequencing exercise in 2021, accounting for 56% of whole employment at websites engaged in genomics actions. Employment in websites specialising in sequencing has greater than greater than doubled between 2009 and 2021 regardless of seeing decreases between 2015 and 2017.

An additional 30% of individuals employed at websites concerned in genomics exercise had been employed in websites engaged within the utility of genomics (the method of immediately utilizing genomic data to enhance focusing on of medical providers), which is split into diagnostics, medical providers and drug improvement. This space has additionally seen substantial rises between 2009 and 2021 with a 16% enhance in employment between 2020 and 2021.

Determine 19: employment at websites engaged in genomic exercise

The worth of turnover generated by genomics websites in 2021 was £2.5 billion, a rise of two% in comparison with 2020. Turnover, by way of actual costs, has been broadly secure between 2019 and 2021 following a pointy upward pattern between 2014 and 2019. Turnover in 2019 was greater than 5 occasions greater than the turnover generated in 2014.

Websites endeavor sequencing exercise, which incorporates sub-categories of consumables, devices and providers, generated the very best turnover of all actions in 2021. These websites generated £2.3 billion in turnover in 2021, accounting for 91% of all turnover generated by websites engaged in genomics actions. Turnover generated from websites specialising in sequencing persistently accounted for almost all of turnover generated from all genomics websites for the interval 2009 to 2021.

Determine 20: turnover generated from websites engaged in genomics exercise

10. Measurement and possession of life sciences companies

10.1 Enterprise measurement

On this publication, the accuracy and protection of small and medium-sized enterprise (SME) classification has been improved. These enhancements have been utilized to the SME standing for companies in 2021 information solely. It’s anticipated that this work shall be utilized to earlier years within the dataset in future publications. Corporations are categorised as SME or non-SME utilizing the European Union normal definition of small and medium-sized enterprises.

In 2021, there have been 5,854 websites that had been a part of SMEs within the UK, which accounted for 77% of all life sciences websites. These websites generated £8.1 billion in turnover (9% of whole turnover generated by the life sciences sector) and employed 68,900 individuals (24% of whole employment within the life sciences sector).

Of all of the websites in 2021, there was a small quantity (0.1%), the place the SME classification was unknown.

The proportion of life sciences websites that had been a part of SMEs varies by area. The East Midlands had the very best proportion of websites that had been part of SMEs, at 81%, in comparison with the South East which had the bottom (72%). The East Midlands equally had the very best proportion of employment at websites belonging to SMEs, at 31%.

Within the South East, 19% of turnover generated within the area was from websites belonging to SMEs, the very best of all areas.

Determine 21: proportion of employment, websites and turnover by SME standing

10.2 Firm possession

On this publication, enhancements have been made to the accuracy and protection of the enterprise possession classification within the dataset. These enhancements have been utilized to the possession for companies in 2021 information solely. It’s anticipated that this work shall be utilized to earlier years within the dataset in future publications.

The information sources used to compile this report comprise data on the final word world proprietor of the companies within the database. This data is accessible for 70% (5,344) of the websites with information referring to 2021. Nonetheless, the websites the place the proprietor origin will not be identified account for a small proportion of whole business employment (7%) and turnover (2%).

In 2021, 26% of life sciences websites had been recognized as being owned by abroad corporations. Nonetheless, it’s essential to notice that the proprietor origin was unknown for a considerable proportion of websites (30%). The websites that had been recognized as having abroad possession accounted for 68% of whole life sciences business turnover and 55% of employment in 2021.

Determine 22 proportion of employment, websites and turnover by firm possession

11. Terminology

Trade: used to collectively describe all sectors coated within the evaluation used within the BaHTSS sequence.

Principal sector: The highest degree of the segmentation scheme used to explain biopharmaceuticals and medical know-how.

Sector: used to explain the 4 element sectors of the life sciences business. This consists of the core biopharmaceutical, core medical know-how, biopharmaceutical service and provide and medical know-how service and provide sectors.

Section: used to explain the person services or products teams inside a sector. See the background high quality and person information part “10. Sector and segmentation classification scheme” for extra particulars on these segments.

Core biopharmaceutical sector: consists of all companies concerned in growing and/or producing their very own pharmaceutical merchandise – from small, analysis and improvement (R&D) targeted biotechs to multinational Massive Pharma.

Biopharmaceutical service and provide sector: includes companies that supply items and providers to core biopharmaceutical companies together with, for instance, Contract Analysis and Manufacturing Organisations (CRMOs), and suppliers of consumables and reagents for R&D services.

Core medical know-how sector: consists of all companies whose major enterprise entails growing and producing medical know-how merchandise, starting from single-use consumables to complicated hospital gear, together with digital well being merchandise.

Medical know-how service and provide sector: includes companies that supply providers to core medical know-how companies together with, for instance, CRMOs, and suppliers of consumables and reagents for R&D services.

Genomics: an interdisciplinary subject specializing in the research of the human genome and the applying of ensuing information to human well being. It’s a cross-cutting categorisation throughout all 4 sectors.

Enterprise: used to explain an entity that’s the authorized proprietor of a bunch of buying and selling addresses or websites and authorized entities. A enterprise might encompass a couple of web site or registered firm. The time period enterprise is used on this doc when discussing the entire life sciences business and the 4 sectors.

Websites: Companies can function over a number of websites over totally different areas within the UK. Every particular person web site is segmented and has employment and turnover assigned to it.

SME standing: primarily based on the European definition of small and medium-sized enterprises (SMEs) and refers to companies with fewer than 250 staff and which both have annual turnover as much as and together with €50m and/or have an annual steadiness sheet whole as much as and together with €43m.