A humorous factor occurred to me just a few months in the past.
Within the midst of a second bout of COVID, each morning I began consuming a cup of sizzling chocolate constructed from ceremonial cacao, the unprocessed paste of fermented beans from the cacao tree, which had been lurking in the back of my cabinet. I can’t actually say whether or not the nice and cozy comforting brew affected the trajectory of the virus. However fairly than feeling down within the dumps and sorry for myself (my common default mode when in poor health), I used to be truly positively cheerful.
As post-COVID life resumed, I made a decision to hold on with my morning cacao ritual. To my shock (and delight), not solely did my good temper proceed however I felt brimming with vitality and had no additional have to kickstart my day with a caffeine repair.
As somebody who’s teetered on the sting of antidepressants for years, this was an attention-grabbing and noteworthy sensation that continues on the time of writing. Furthermore, the guts metrics on my scales confirmed that my pulse wave velocity (a measurement of arterial stiffness and coronary heart well being) and total vascular age have been transferring in a downwards trajectory. (Transfer over Benjamin Button!)
Past my very own expertise, researchers have been investigating the guts and mind advantages of cacao and its extra processed relations, darkish chocolate and cocoa, for a few years. They’ve centered on cacao beans’ wealthy class of polyphenols known as flavanols, in addition to the alkaloid theobromine, that are the almost definitely culprits for the flexibility of cacao to enhance cognition and coronary heart well being.
Meals of the Gods
Cacao pods develop on the evergreen Theobroma Cacao tree, which is discovered within the equatorial international locations of South America, West Africa, and Asia. For 1000’s of years, it has been revered as a sacred plant and used medicinally. The phrase theobroma finds its origin within the Greek phrase θεός (theos), which means ‘god’, and βρῶμα (broma), which means ‘meals.’
Relationship way back to 1700 BC, cacao was consumed as a sizzling brew in Mesoamerica amongst the Olmec, Aztec, and Mayan civilizations. Certainly, so revered have been cacao beans that they have been even used as foreign money by some. With the arrival of the Spanish within the sixteenth century, the Aztec emperor Montezuma was noticed to drink huge portions of cacao probably due to its purported aphrodisiac properties. The Spanish would finally convey cacao and chocolate again to Europe, with the primary chocolate homes opening in 1657 in London for town’s well-heeled inhabitants searching for the most recent style.
Over the centuries, nevertheless, with developments in mass processing methods and the addition of sugar and milk, cacao’s well being advantages have largely been misplaced and it has grow to be little greater than a confectionery for the sweet-toothed or a romantic gesture on Valentine’s day.
A Trendy-Day Plant Medication
However in plant medication circles, cacao has been making a comeback. UK-based Rebekah Shaman, who has been working with plant medicines for the reason that late nineties, says she obtained the message loud and clear throughout an ayahuasca ceremony that she wanted to convey cacao again to the UK and begin providing it in a ceremonial setting.
On the time Rebekah knew little about cacao, however she understood that “within the West we’ve misplaced ceremony, we’ve misplaced our connection to plant medicines, we’ve misplaced our understanding of nature and the facility of crops.” Undeterred, she flew to Guatemala, gave away most of her possessions, and crammed her rucksack with twenty-one kilos of cacao for her return to Europe.
Drawing on her personal coaching with Shamans within the Amazon, she began providing cacao ceremonies to ease the frazzled nerves of overwhelmed Londoners. The outcomes have been superb. “Individuals have been actually benefiting from taking cacao frequently with it serving to to shift delicate melancholy, stress, and nervousness,” Rebekah recollects. Quickly she launched her personal enterprise importing cacao from Peru and Ecuador.
Right this moment cacao ceremonies are all over the place. From yoga retreats to ecstatic dance, cacao is now being consumed by religious seekers for improved temper, emotions of bliss, and its coronary heart opening powers.
The Science of Cacao
To the hard-nosed scientists amongst us, this all could sound fairly too “woo woo” to be taken significantly. However within the lab, cacao’s results on elevated blood circulation, each to the guts and the mind, are thought to play a serious function within the purported well being advantages of this historical treatment.
To date, researchers have centered on two key flavanols present in cacao, epicatechin and catechin, plus theobromine. Like caffeine, which can be present in small quantities, theobromine is a methylxanthine (a bronchodilator and delicate stimulant).1 Regardless of studies from common cacao shoppers of alleviation of low temper, stress, and nervousness, researchers have primarily centered on whether or not the flavanols and theobromine might need some form of neuroprotective impact on the mind, with the corollaries of enhancing cognition, focus, and reminiscence. In a single examine, mice fed a theobromine-rich weight loss program carried out cognitively higher in duties than the non-theobrome group.2
Caffeine and theobromine are each vasodilators via the inhibition of adenosine receptors.3 However in comparison with its methylxanthine cousin caffeine, theobromine doesn’t look like addictive, maybe resulting from its longer half-life4; a brief half-life implies stronger withdrawal signs.
Cacao additionally comprises magnesium, copper, chromium, and different minerals, in addition to varied amines – serotonin, tryptophan, phenylethylamine, tyrosine, tryptamine, and tyramine. However the jury continues to be out whether or not the amines have any actual impact as they’re damaged down within the intestine, liver, and kidneys by monoamine oxidase enzymes.
And there’s additionally a small quantity of anandamide,5 the endocannabinoid, in cacao. But it surely’s not clear whether or not anandamide is current in adequate portions to work together with the endocannabinoid system in any significant manner.

Cacao and the Mind
Other than nourishing our intestine microbiome, most plant-based meals are wealthy in flavonoids, which if consumed recurrently, could assist to lower the danger of dementia.6 (A flavonol is a kind of flavonoid discovered in lots of fruit and veggies.) With information already linking the each day consumption of chocolate to decrease cognitive decline,7 it’s thought that the neuroprotective results of flavonoids and promotion of neurogenesis could contribute to their total neurobiological advantages for the mind.8
As vasodilators, these dietary compounds additionally enhance the perform of the endothelium, the skinny membrane lining the within of the guts and blood vessels, by growing nitric oxide bioavailability. Flavonoids not solely assist regulate blood stress, but additionally enhance cerebral blood circulation, and this will assist to elucidate why cacao seems to be so good for each our coronary heart and our mind, which in spite of everything are intimately related.9
Analysis evaluating the each day administration of chocolate infused with low (48mg), medium (520mg), and excessive (993mg) quantities of flavanols to aged topics – some with delicate cognitive impairment,10 others with out11– confirmed larger ranges of flavanols led to superior enhancements in processing velocity, govt perform, and dealing reminiscence in each teams. (Nevertheless, a lately revealed examine in older ladies and men evaluating a cocoa complement containing 500mg of flavanols, with a placebo, and a commercially obtainable multivitamin, discovered solely the multivitamin improved their cognition.)12
It’s noteworthy that insulin resistance, blood stress, and lipid peroxidation (the cell damaging course of by which free radicals steal electrons in cell membranes) have been all diminished in members within the excessive and intermediate-flavanol teams. Elevated blood circulation within the dentate gyrus of the hippocampus, a mind construction notably affected by ageing, after excessive cocoa flavanol consumption, could account for enhancements in reminiscence.13
Different analysis seems to hyperlink impaired cerebral blood circulation with melancholy14 and will increase in cerebral blood circulation with enhancements in depressive states following remedy with antidepressants.15
Cacao for Coronary heart Well being
Cardiovascular illnesses are the main explanation for dying globally. Together with way of life measures reminiscent of giving up smoking and getting extra train, weight loss program is considered a key issue to enhancing cardiovascular well being.
Flavonoids present in fruit and greens positively impression our coronary heart well being not solely via their antioxidant motion but additionally by facilitating vasodilation, regulating apoptotic processes within the endothelium, and lowering irritation.16
Research have discovered that each flavanols in cacao, catechin and epicatechin, enhance cardiovascular perform, decreasing blood stress17 and lowering arterial stiffness. One current examine18 confirmed that administering flavanol wealthy cocoa over eight days in wholesome volunteers lowered blood stress in these with considerably elevated blood stress though nonetheless inside the regular vary. Curiously, there was no change in topics whose blood stress was already low.
In one other examine,19 sufferers with hypertension discovered that consuming 100 grams of darkish chocolate containing 88mg of flavonols did the triple whammy of decreasing blood stress, insulin resistance, and LDL ldl cholesterol (the so-called dangerous ldl cholesterol).
Actually, the ldl cholesterol enhancing advantages of consuming darkish chocolate20 go even additional with researchers discovering it not solely lowered LDL but additionally elevated good ldl cholesterol (HDL), in all chance as a result of successful mixture of the flavanols and theobromine.
However a randomized trial21 evaluating cocoa with typical ranges of theobromine (150mg) and 850mg of pure theobromine discovered that solely the excessive dose of pure theobromine modified levels of cholesterol. A phrase of warning concerning the overconsumption of theobromine: will increase in cerebral blood circulation can set off migraines in some folks and consuming excessive ranges of theobromine could cause nausea, lack of urge for food, complications and detrimental temper modifications. Theobromine can be the compound accountable for the toxicity of chocolate to canine.

Attainable Drug Interactions
It’s simple to get enthusiastic about the advantages of cacao for our total well being. Nevertheless, some care is required when consuming ceremonial grade cacao paste, which is minimally processed and subsequently retains larger ranges of the naturally occurring compounds, a few of which can trigger drug interactions.
As beforehand talked about, cacao comprises serotonin (and tryptophan, its precursor). For anybody taking Monoamine Oxidase Inhibitor Medicine (generally prescribed for melancholy), cacao is probably not advisable. MAO inhibitors work by inhibiting the breakdown of a variety of neurotransmitters within the physique, together with serotonin.
MAO inhibitors may also stop the breakdown of the serotonin present in cacao, which may enhance the neurotransmitter to harmful ranges, doubtlessly inflicting “serotonin syndrome,” with signs reminiscent of agitation, insomnia, confusion, lack of muscle coordination, and muscle twitching. (Sure, it’s potential to have an excessive amount of serotonin).
Moreover, MAO inhibitors inhibit the breakdown of tyramine,22 additionally present in cacao. Overly excessive ranges of tyramine could cause sudden will increase in blood stress and migraines, which is why sufferers on MAO inhibitors ought to keep away from tyramine-rich meals (reminiscent of sturdy cheeses, cured meats, and over-ripe fruits).
There’s additionally a college of thought that the tetrahydro‐β‐carbolines23 present in cacao are themselves naturally occurring MAO inhibitors. In addition to doubtlessly contributing to cacao’s antidepressant impact, the presence of those compounds could enhance the potential for drug interactions if one is taking antidepressants, together with SSRIs (Selective Serotonin Reuptake Inhibitors), though this has but to be absolutely investigated. It most likely signifies that anybody prescribed serotonin-boosting antidepressants ought to keep away from excessive doses of unprocessed cacao merchandise.
For many of us although, whether or not we devour ceremonial cacao as a morning ritual to set intentions for the day, or if we merely eat a few items of high quality darkish chocolate derived from fair-trade sustainably sourced cacao, there actually is little to lose and lots to realize by partaking of the sacred plant medication from the theobroma cacao tree.
To listen to Rebekah Shaman’s interview with Mary Biles, take a look at the podcast Hashish Voices.
Mary Biles, a UK-based journalist, educator, and Mission CBD contributing author, is the writer of The CBD Ebook (Harper Collins, UK). Copyright, Mission CBD. Will not be reprinted with out permission.
Footnotes
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